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Comprehensive metabolic modeling of multiple (13)C-isotopomer data sets to study metabolism in perfused working hearts
In many forms of cardiomyopathy, alterations in energy substrate metabolism play a key role in disease pathogenesis. Stable isotope tracing in rodent heart perfusion systems can be used to determine cardiac metabolic fluxes, namely those relative fluxes that contribute to pyruvate, the acetyl-CoA po...
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| Publicado no: | Am J Physiol Heart Circ Physiol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5114467/ https://ncbi.nlm.nih.gov/pubmed/27496880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00428.2016 |
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