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Rational design of (13)C-labeling experiments for metabolic flux analysis in mammalian cells

BACKGROUND: (13)C-Metabolic flux analysis ((13)C-MFA) is a standard technique to probe cellular metabolism and elucidate in vivo metabolic fluxes. (13)C-Tracer selection is an important step in conducting (13)C-MFA, however, current methods are restricted to trial-and-error approaches, which commonl...

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Autors principals: Crown, Scott B, Ahn, Woo Suk, Antoniewicz, Maciek R
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490712/
https://ncbi.nlm.nih.gov/pubmed/22591686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-6-43
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