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An Unbiased Mass Spectrometry Approach Identifies Glypican-3 as an Interactor of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) and Low Density Lipoprotein Receptor (LDLR) in Hepatocellular Carcinoma Cells

The mechanism of LDL receptor (LDLR) degradation mediated by the proprotein convertase subtilisin/kexin type 9 (PCSK9) has been extensively studied; however, many steps within this process remain unclear and still require characterization. Recent studies have shown that PCSK9 lacking its Cys/His-ric...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Ly, Kévin, Essalmani, Rachid, Desjardins, Roxane, Seidah, Nabil G., Day, Robert
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114417/
https://ncbi.nlm.nih.gov/pubmed/27758865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.746883
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