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Thrombin Cleavage of Inter-α-inhibitor Heavy Chain 1 Regulates Leukocyte Binding to an Inflammatory Hyaluronan Matrix

Dynamic alterations of the extracellular matrix in response to injury directly modulate inflammation and consequently the promotion and resolution of disease. During inflammation, hyaluronan (HA) is increased at sites of inflammation where it may be covalently modified with the heavy chains (HC) of...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Petrey, Aaron C., de la Motte, Carol A.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114391/
https://ncbi.nlm.nih.gov/pubmed/27679489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.755660
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