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A stable isotope method for in vivo assessment of human insulin synthesis and secretion

AIMS: In vitro, beta cells immediately secrete stored but readily releasable insulin in response to a rise of glucose. During a prolonged insulin response, this is followed by newly synthesized insulin. Our aim was to develop an in vivo test to determine the ratio between readily available and newly...

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Publicado en:Acta Diabetol
Autores principales: Jainandunsing, Sjaam, van Miert, Joram N. I., Rietveld, Trinet, Darcos Wattimena, J. L., Sijbrands, Eric J. G., de Rooij, Felix W. M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Milan 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114334/
https://ncbi.nlm.nih.gov/pubmed/27552831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00592-016-0896-3
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