Recombinant Lipoprotein Rv1016c Derived from Mycobacterium tuberculosis Is a TLR-2 Ligand that Induces Macrophages Apoptosis and Inhibits MHC II Antigen Processing

TLR2-dependent cellular signaling in Mycobacterium tuberculosis-infected macrophages causes apoptosis and inhibits class II major histocompatibility complex (MHC-II) molecules antigen processing, leading to evasion of surveillance. Mycobacterium tuberculosis (MTB) lipoproteins are an important class...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Su, Haibo, Zhu, Shenglin, Zhu, Lin, Huang, Wei, Wang, Honghai, Zhang, Zhi, Xu, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114242/
https://ncbi.nlm.nih.gov/pubmed/27917375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2016.00147
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