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Fanconi Anemia: a DNA Repair Disorder Characterized by Accelerated Decline of the Hematopoietic Stem Cell Compartment and Other Features of Aging
Fanconi Anemia (FA) is a rare autosomal genetic disorder characterized by progressive bone marrow failure (BMF), endocrine dysfunction, cancer, and other clinical features commonly associated with normal aging. The anemia stems directly from an accelerated decline of the hematopoietic stem cell comp...
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| Опубликовано в: : | Ageing Res Rev |
|---|---|
| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5114166/ https://ncbi.nlm.nih.gov/pubmed/27223997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.arr.2016.05.005 |
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