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p62 in cancer: signaling adaptor beyond autophagy
Adaptor proteins participate in selective autophagy, which is critical for cellular detoxification and stress relief. However, new evidence supports an autophagy-independent key role of the adaptor p62 (encoded by the gene Sqstm1) in signaling functions central to tumor initiation in the epithelium,...
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| Udgivet i: | Cell |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5114003/ https://ncbi.nlm.nih.gov/pubmed/27768885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.09.030 |
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