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p62 in cancer: signaling adaptor beyond autophagy

Adaptor proteins participate in selective autophagy, which is critical for cellular detoxification and stress relief. However, new evidence supports an autophagy-independent key role of the adaptor p62 (encoded by the gene Sqstm1) in signaling functions central to tumor initiation in the epithelium,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell
Prif Awduron: Moscat, Jorge, Karin, Michael, Diaz-Meco, Maria T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114003/
https://ncbi.nlm.nih.gov/pubmed/27768885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.09.030
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