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p62 at the Crossroads of Autophagy, Apoptosis, and Cancer
The signaling adaptor p62 is a multidomain protein implicated in the activation of the transcription factor NF-κB. Recent findings link p62 activity to the extrinsic apoptosis pathway, and Mathew et al. (2009) now show that the modulation of p62 by autophagy is a key factor in tumorigenesis. These f...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3971861/ https://ncbi.nlm.nih.gov/pubmed/19524504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.05.023 |
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