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Trypanosoma brucei CYP51: Essentiality and Targeting Therapy in an Experimental Model

Trypanosoma brucei gambiense is the main causative agent of Human African Trypanosomiasis (HAT), also known as sleeping sickness. Because of limited alternatives and treatment toxicities, new therapeutic options are urgently needed for patients with HAT. Sterol 14alpha-demethylase (CYP51) is a poten...

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Detalles Bibliográficos
Publicado en:PLoS Negl Trop Dis
Main Authors: Dauchy, Frédéric-Antoine, Bonhivers, Mélanie, Landrein, Nicolas, Dacheux, Denis, Courtois, Pierrette, Lauruol, Florian, Daulouède, Sylvie, Vincendeau, Philippe, Robinson, Derrick R.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113867/
https://ncbi.nlm.nih.gov/pubmed/27855164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005125
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