Trypanosoma brucei CYP51: Essentiality and Targeting Therapy in an Experimental Model

Trypanosoma brucei gambiense is the main causative agent of Human African Trypanosomiasis (HAT), also known as sleeping sickness. Because of limited alternatives and treatment toxicities, new therapeutic options are urgently needed for patients with HAT. Sterol 14alpha-demethylase (CYP51) is a poten...

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Vydáno v:PLoS Negl Trop Dis
Hlavní autoři: Dauchy, Frédéric-Antoine, Bonhivers, Mélanie, Landrein, Nicolas, Dacheux, Denis, Courtois, Pierrette, Lauruol, Florian, Daulouède, Sylvie, Vincendeau, Philippe, Robinson, Derrick R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113867/
https://ncbi.nlm.nih.gov/pubmed/27855164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005125
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