Trypanosoma brucei CYP51: Essentiality and Targeting Therapy in an Experimental Model

Trypanosoma brucei gambiense is the main causative agent of Human African Trypanosomiasis (HAT), also known as sleeping sickness. Because of limited alternatives and treatment toxicities, new therapeutic options are urgently needed for patients with HAT. Sterol 14alpha-demethylase (CYP51) is a poten...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Dauchy, Frédéric-Antoine, Bonhivers, Mélanie, Landrein, Nicolas, Dacheux, Denis, Courtois, Pierrette, Lauruol, Florian, Daulouède, Sylvie, Vincendeau, Philippe, Robinson, Derrick R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113867/
https://ncbi.nlm.nih.gov/pubmed/27855164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005125
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