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(1)H‐Detected Solid‐State NMR Studies of Water‐Inaccessible Proteins In Vitro and In Situ

(1)H detection can significantly improve solid‐state NMR spectral sensitivity and thereby allows studying more complex proteins. However, the common prerequisite for (1)H detection is the introduction of exchangeable protons in otherwise deuterated proteins, which has thus far significantly hampered...

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Publicat a:Angew Chem Int Ed Engl
Autors principals: Medeiros‐Silva, João, Mance, Deni, Daniëls, Mark, Jekhmane, Shehrazade, Houben, Klaartje, Baldus, Marc, Weingarth, Markus
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113794/
https://ncbi.nlm.nih.gov/pubmed/27671832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201606594
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