Supramolecular Control over Split‐Luciferase Complementation

Supramolecular split‐enzyme complementation restores enzymatic activity and allows for on–off switching. Split‐luciferase fragment pairs were provided with an N‐terminal FGG sequence and screened for complementation through host‐guest binding to cucurbit[8]uril (Q8). Split‐luciferase heterocomplex f...

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Publicat a:Angew Chem Int Ed Engl
Autors principals: Bosmans, Ralph P. G., Briels, Jeroen M., Milroy, Lech‐Gustav, de Greef, Tom F. A., Merkx, Maarten, Brunsveld, Luc
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113697/
https://ncbi.nlm.nih.gov/pubmed/27356091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201602807
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