Supramolecular Control over Split‐Luciferase Complementation

Supramolecular split‐enzyme complementation restores enzymatic activity and allows for on–off switching. Split‐luciferase fragment pairs were provided with an N‐terminal FGG sequence and screened for complementation through host‐guest binding to cucurbit[8]uril (Q8). Split‐luciferase heterocomplex f...

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Bibliographic Details
Published in:Angew Chem Int Ed Engl
Main Authors: Bosmans, Ralph P. G., Briels, Jeroen M., Milroy, Lech‐Gustav, de Greef, Tom F. A., Merkx, Maarten, Brunsveld, Luc
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
Subjects:
Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113697/
https://ncbi.nlm.nih.gov/pubmed/27356091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201602807
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