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PDGFRα signalling promotes fibrogenic responses in collagen‐producing cells in Duchenne muscular dystrophy

Fibrosis is a characteristic of Duchenne muscular dystrophy (DMD), yet the cellular and molecular mechanisms responsible for DMD fibrosis are poorly understood. Utilizing the Collagen1a1‐GFP transgene to identify cells producing Collagen‐I matrix in wild‐type mice exposed to toxic injury or those mu...

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Dettagli Bibliografici
Pubblicato in:J Pathol
Autori principali: Ieronimakis, Nicholas, Hays, Aislinn, Prasad, Amalthiya, Janebodin, Kajohnkiart, Duffield, Jeremy S, Reyes, Morayma
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Ltd 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113675/
https://ncbi.nlm.nih.gov/pubmed/27569721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4801
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