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The rise and fall of the D-serine-mediated gliotransmission hypothesis

D-Serine modulates NMDA receptors and regulates synaptic plasticity, neurodevelopment, and learning and memory. However, the primary site of D-serine synthesis and release remains controversial, with some arguing that it is a “gliotransmitter” and others defining it as a “neuronal co-transmitter”. R...

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Detalhes bibliográficos
Publicado no:Trends Neurosci
Main Authors: Wolosker, Herman, Balu, Darrick T., Coyle, Joseph T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113294/
https://ncbi.nlm.nih.gov/pubmed/27742076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tins.2016.09.007
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