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Neuronal D-serine regulates dendritic architecture in the somatosensory cortex

D-serine, which is synthesized by the enzyme serine racemase (SR), is a co-agonist at the N-methyl-D-aspartate receptor (NMDAR). In an animal model of NMDAR hypofunction, the constitutive SR knockout (SR−/−) mouse, pyramidal neurons in primary somatosensory cortex (S1) had reductions in the complexi...

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Detalhes bibliográficos
Main Authors: Balu, Darrick T., Coyle, Joseph T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400345/
https://ncbi.nlm.nih.gov/pubmed/22521586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2012.04.020
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