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Local Inhibition of Complement Improves Mesenchymal Stem Cell Viability and Function After Administration
The results of recent clinical trials using mesenchymal stem cells (MSCs) have been unsatisfactory, indicating that current MSC-based therapies need to be improved. We and others have previously demonstrated that MSCs activate complement by unknown mechanisms after infusion, leading to damaged MSCs....
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| 發表在: | Mol Ther |
|---|---|
| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5113108/ https://ncbi.nlm.nih.gov/pubmed/27377042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2016.142 |
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