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Local Inhibition of Complement Improves Mesenchymal Stem Cell Viability and Function After Administration

The results of recent clinical trials using mesenchymal stem cells (MSCs) have been unsatisfactory, indicating that current MSC-based therapies need to be improved. We and others have previously demonstrated that MSCs activate complement by unknown mechanisms after infusion, leading to damaged MSCs....

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Detalles Bibliográficos
Publicado en:Mol Ther
Main Authors: Li, Yan, Fung, John, Lin, Feng
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113108/
https://ncbi.nlm.nih.gov/pubmed/27377042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2016.142
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