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Local Inhibition of Complement Improves Mesenchymal Stem Cell Viability and Function After Administration

The results of recent clinical trials using mesenchymal stem cells (MSCs) have been unsatisfactory, indicating that current MSC-based therapies need to be improved. We and others have previously demonstrated that MSCs activate complement by unknown mechanisms after infusion, leading to damaged MSCs....

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Publicado en:Mol Ther
Autores principales: Li, Yan, Fung, John, Lin, Feng
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113108/
https://ncbi.nlm.nih.gov/pubmed/27377042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2016.142
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