Diversification in the HIV-1 Envelope Hyper-variable Domains V2, V4, and V5 and Higher Probability of Transmitted/Founder Envelope Glycosylation Favor the Development of Heterologous Neutralization Breadth

A recent study of plasma neutralization breadth in HIV-1 infected individuals at nine International AIDS Vaccine Initiative (IAVI) sites reported that viral load, HLA-A*03 genotype, and subtype C infection were strongly associated with the development of neutralization breadth. Here, we refine the f...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Smith, S. Abigail, Burton, Samantha L., Kilembe, William, Lakhi, Shabir, Karita, Etienne, Price, Matt, Allen, Susan, Hunter, Eric, Derdeyn, Cynthia A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5112890/
https://ncbi.nlm.nih.gov/pubmed/27851829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005989
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