STAT3 Inhibition as a Therapeutic Strategy for Chordoma

Objective Signal transducer and activator of transcription (STAT) proteins regulate key cellular fate decisions including proliferation and apoptosis. STAT3 overexpression induces tumor growth in multiple neoplasms. STAT3 is constitutively activated in chordoma, a tumor with a high recurrence rate d...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Neurol Surg B Skull Base
Autori principali: Wang, Anthony C., Owen, John H., Abuzeid, Waleed M., Hervey-Jumper, Shawn L., He, Xiaobing, Gurrea, Mikel, Lin, Meijuan, Altshuler, David B., Keep, Richard F., Prince, Mark E., Carey, Thomas E., Fan, Xing, McKean, Erin L., Sullivan, Stephen E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Georg Thieme Verlag KG 2016
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5112170/
https://ncbi.nlm.nih.gov/pubmed/27857879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0036-1584198
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi