STAT3 Inhibition as a Therapeutic Strategy for Chordoma

Objective Signal transducer and activator of transcription (STAT) proteins regulate key cellular fate decisions including proliferation and apoptosis. STAT3 overexpression induces tumor growth in multiple neoplasms. STAT3 is constitutively activated in chordoma, a tumor with a high recurrence rate d...

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Bibliografiske detaljer
Udgivet i:J Neurol Surg B Skull Base
Main Authors: Wang, Anthony C., Owen, John H., Abuzeid, Waleed M., Hervey-Jumper, Shawn L., He, Xiaobing, Gurrea, Mikel, Lin, Meijuan, Altshuler, David B., Keep, Richard F., Prince, Mark E., Carey, Thomas E., Fan, Xing, McKean, Erin L., Sullivan, Stephen E.
Format: Artigo
Sprog:Inglês
Udgivet: Georg Thieme Verlag KG 2016
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5112170/
https://ncbi.nlm.nih.gov/pubmed/27857879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0036-1584198
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