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STAT3 Inhibition as a Therapeutic Strategy for Chordoma
Objective Signal transducer and activator of transcription (STAT) proteins regulate key cellular fate decisions including proliferation and apoptosis. STAT3 overexpression induces tumor growth in multiple neoplasms. STAT3 is constitutively activated in chordoma, a tumor with a high recurrence rate d...
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Publicado no: | J Neurol Surg B Skull Base |
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Main Authors: | , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Georg Thieme Verlag KG
2016
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5112170/ https://ncbi.nlm.nih.gov/pubmed/27857879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0036-1584198 |
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