Boosting Central Nervous System Axon Regeneration by Circumventing Limitations of Natural Cytokine Signaling

Retinal ganglion cells (RGCs) do not normally regenerate injured axons, but die upon axotomy. Although IL-6-like cytokines are reportedly neuroprotective and promote optic nerve regeneration, their overall regenerative effects remain rather moderate. Here, we hypothesized that direct activation of t...

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Publicat a:Mol Ther
Autors principals: Leibinger, Marco, Andreadaki, Anastasia, Gobrecht, Philipp, Levin, Evgeny, Diekmann, Heike, Fischer, Dietmar
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5112033/
https://ncbi.nlm.nih.gov/pubmed/27203446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2016.102
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