APC/C and SCF(Cyclin F) constitute a reciprocal feedback circuit controlling S-phase entry

The Anaphase Promoting Complex/Cyclosome (APC/C) is an ubiquitin ligase and core component of the cell cycle oscillator. During G1-phase APC/C binds to its substrate receptor Cdh1 and APC/C(Cdh1) plays an important role in restricting S-phase entry and maintaining genome integrity. We describe a rec...

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Publicado en:Cell Rep
Autores principales: Choudhury, Rajarshi, Bonacci, Thomas, Arceci, Anthony, Lahiri, Debojyoti, Mills, Christine A, Kernan, Jennifer L, Branigan, Timothy B, DeCaprio, James A, Burke, Daniel J, Emanuele, Michael J
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111906/
https://ncbi.nlm.nih.gov/pubmed/27653696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.08.058
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