Charge neutralization as the major factor for the assembly of nucleocapsid-like particles from C-terminal truncated hepatitis C virus core protein

BACKGROUND: Hepatitis C virus (HCV) core protein, in addition to its structural role to form the nucleocapsid assembly, plays a critical role in HCV pathogenesis by interfering in several cellular processes, including microRNA and mRNA homeostasis. The C-terminal truncated HCV core protein (C124) is...

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Veröffentlicht in:PeerJ
Hauptverfasser: de Souza, Theo Luiz Ferraz, de Lima, Sheila Maria Barbosa, Braga, Vanessa L. de Azevedo, Peabody, David S., Ferreira, Davis Fernandes, Bianconi, M. Lucia, Gomes, Andre Marco de Oliveira, Silva, Jerson Lima, de Oliveira, Andréa Cheble
Format: Artigo
Sprache:Inglês
Veröffentlicht: PeerJ Inc. 2016
Schlagworte:
Biochemistry
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111903/
https://ncbi.nlm.nih.gov/pubmed/27867765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.2670
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