Charge neutralization as the major factor for the assembly of nucleocapsid-like particles from C-terminal truncated hepatitis C virus core protein

BACKGROUND: Hepatitis C virus (HCV) core protein, in addition to its structural role to form the nucleocapsid assembly, plays a critical role in HCV pathogenesis by interfering in several cellular processes, including microRNA and mRNA homeostasis. The C-terminal truncated HCV core protein (C124) is...

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Detalhes bibliográficos
Publicado no:PeerJ
Main Authors: de Souza, Theo Luiz Ferraz, de Lima, Sheila Maria Barbosa, Braga, Vanessa L. de Azevedo, Peabody, David S., Ferreira, Davis Fernandes, Bianconi, M. Lucia, Gomes, Andre Marco de Oliveira, Silva, Jerson Lima, de Oliveira, Andréa Cheble
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2016
Assuntos:
Biochemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111903/
https://ncbi.nlm.nih.gov/pubmed/27867765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.2670
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