Charge neutralization as the major factor for the assembly of nucleocapsid-like particles from C-terminal truncated hepatitis C virus core protein

BACKGROUND: Hepatitis C virus (HCV) core protein, in addition to its structural role to form the nucleocapsid assembly, plays a critical role in HCV pathogenesis by interfering in several cellular processes, including microRNA and mRNA homeostasis. The C-terminal truncated HCV core protein (C124) is...

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Détails bibliographiques
Publié dans:PeerJ
Auteurs principaux: de Souza, Theo Luiz Ferraz, de Lima, Sheila Maria Barbosa, Braga, Vanessa L. de Azevedo, Peabody, David S., Ferreira, Davis Fernandes, Bianconi, M. Lucia, Gomes, Andre Marco de Oliveira, Silva, Jerson Lima, de Oliveira, Andréa Cheble
Format: Artigo
Langue:Inglês
Publié: PeerJ Inc. 2016
Sujets:
Biochemistry
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111903/
https://ncbi.nlm.nih.gov/pubmed/27867765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.2670
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