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Modelling and Analysis of Intercalant Effects on Circular DNA Conformation

The large-scale conformation of DNA molecules play a critical role in many basic elements of cellular functionality and viability. By targeting the structural properties of DNA, many cancer drugs, such as anthracyclines, effectively inhibit tumor growth, but can also produce dangerous side effects....

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Detalhes bibliográficos
Publicado no:ACS Nano
Main Authors: Krueger, Eric, Shim, Jiwook, Fathizadeh, Arman, Chang, A. Nicole, Subei, Basheer, Yocham, Katie M., Davis, Paul H., Graugnard, Elton, Khalili-Araghi, Fatemeh, Bashir, Rashid, Estrada, David, Fologea, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111899/
https://ncbi.nlm.nih.gov/pubmed/27559753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.6b04876
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