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A swine model of acute thrombocytopenia with prolonged bleeding time produced by busulfan

Animal models of thrombocytopenia are indispensable for evaluating the in vivo efficacy of hemostatic agents, cryopreserved platelets, and artificial platelets, but no large animal models are available. In this study, we generated a swine model of acute thrombocytopenia with prolonged bleeding times...

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Detalhes bibliográficos
Publicado no:Exp Anim
Main Authors: Abe, Tomoyuki, Kono, Shota, Ohnuki, Takahiro, Hishikawa, Shuji, Kunita, Satoshi, Hanazono, Yutaka
Formato: Artigo
Idioma:Inglês
Publicado em: Japanese Association for Laboratory Animal Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111837/
https://ncbi.nlm.nih.gov/pubmed/27333841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1538/expanim.16-0022
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