MHC-Matched Induced Pluripotent Stem Cells Can Attenuate Cellular and Humoral Immune Responses but Are Still Susceptible to Innate Immunity in Pigs

Recent studies have revealed negligible immunogenicity of induced pluripotent stem (iPS) cells in syngeneic mice and in autologous monkeys. Therefore, human iPS cells would not elicit immune responses in the autologous setting. However, given that human leukocyte antigen (HLA)-matched allogeneic iPS...

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Bibliografiske detaljer
Main Authors: Mizukami, Yoshihisa, Abe, Tomoyuki, Shibata, Hiroaki, Makimura, Yukitoshi, Fujishiro, Shuh-hei, Yanase, Kimihide, Hishikawa, Shuji, Kobayashi, Eiji, Hanazono, Yutaka
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057111/
https://ncbi.nlm.nih.gov/pubmed/24927426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098319
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