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Melting of duplex DNA in the absence of ATP by NS3 helicase domain through specific interaction with a single-strand/double-strand junction

Helicases unwind double-stranded nucleic acids, remove secondary structures from single-stranded nucleic acids, and remove proteins bound to nucleic acids. For many helicases, the mechanisms for these different functions share the ability to translocate with a directional bias as a result of ATP bin...

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Publicat a:Biochemistry
Autors principals: Reynolds, Kimberly A., Cameron, Craig E., Raney, Kevin D.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111830/
https://ncbi.nlm.nih.gov/pubmed/26091150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00214
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