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Mouse Models of Stargardt 3 Dominant Macular Degeneration
Stargardt type 3 macular degeneration is dependent on a dominant defect in a single gene, ELOVL4 (elongase of very long chain fatty acids 4). The encoded enzyme, ELOVL4, is required for the synthesis of very long chain polyunsaturated fatty acids (VLC-PUFAs), a rare class of > C24 lipids. In vitr...
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| Udgivet i: | Adv Exp Med Biol |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5111794/ https://ncbi.nlm.nih.gov/pubmed/26427404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-319-17121-0_19 |
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