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Mouse Models of Stargardt 3 Dominant Macular Degeneration

Stargardt type 3 macular degeneration is dependent on a dominant defect in a single gene, ELOVL4 (elongase of very long chain fatty acids 4). The encoded enzyme, ELOVL4, is required for the synthesis of very long chain polyunsaturated fatty acids (VLC-PUFAs), a rare class of > C24 lipids. In vitr...

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Bibliografske podrobnosti
izdano v:Adv Exp Med Biol
Main Authors: Barabas, Peter, Gorusupudi, Aruna, Bernstein, Paul S, Krizaj, David
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111794/
https://ncbi.nlm.nih.gov/pubmed/26427404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-319-17121-0_19
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