Role of ELOVL4 and very long-chain polyunsaturated fatty acids in mouse models of Stargardt type 3 retinal degeneration

Stargardt type 3 (STGD3) disease is a juvenile macular dystrophy caused by mutations in the ELOVL4 (Elongation of very long chain fatty acids 4) gene. Its protein product, ELOVL4, is an elongase required for the biosynthesis of very long-chain polyunsaturated fatty acids (VLC-PUFAs). It is unclear w...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Barabas, Peter, Liu, Aihua, Xing, Wei, Chen, Ching-Kang, Tong, Zongzhong, Watt, Carl B., Jones, Bryan W., Bernstein, Paul S., Križaj, David
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2013
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612655/
https://ncbi.nlm.nih.gov/pubmed/23479632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1214707110
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