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Calculating the fetal fraction for noninvasive prenatal testing based on genome‐wide nucleosome profiles

OBJECTIVE: While large fetal copy number aberrations can generally be detected through sequencing of DNA in maternal blood, the reliability of tests depends on the fraction of DNA that originates from the fetus. Existing methods to determine this fetal fraction require additional work or are limited...

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Dades bibliogràfiques
Publicat a:Prenat Diagn
Autors principals: Straver, Roy, Oudejans, Cees B. M., Sistermans, Erik A., Reinders, Marcel J. T.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111749/
https://ncbi.nlm.nih.gov/pubmed/26996738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pd.4816
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