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Calculating the fetal fraction for noninvasive prenatal testing based on genome‐wide nucleosome profiles
OBJECTIVE: While large fetal copy number aberrations can generally be detected through sequencing of DNA in maternal blood, the reliability of tests depends on the fraction of DNA that originates from the fetus. Existing methods to determine this fetal fraction require additional work or are limited...
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| Publié dans: | Prenat Diagn |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley and Sons Inc.
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5111749/ https://ncbi.nlm.nih.gov/pubmed/26996738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pd.4816 |
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