Polymeric nanofiber coating with tunable combinatorial antibiotic delivery prevents biofilm-associated infection in vivo

Bacterial biofilm formation is a major complication of implantable medical devices that results in therapeutically challenging chronic infections, especially in cases involving antibiotic-resistant bacteria. As an approach to prevent these infections, an electrospun composite coating comprised of po...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Ashbaugh, Alyssa G., Jiang, Xuesong, Zheng, Jesse, Tsai, Andrew S., Kim, Woo-Shin, Thompson, John M., Miller, Robert J., Shahbazian, Jonathan H., Wang, Yu, Dillen, Carly A., Ordonez, Alvaro A., Chang, Yong S., Jain, Sanjay K., Jones, Lynne C., Sterling, Robert S., Mao, Hai-Quan, Miller, Lloyd S.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111718/
https://ncbi.nlm.nih.gov/pubmed/27791154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1613722113
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