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Chromosome-refolding model of mating-type switching in yeast

Chromosomes are folded into cells in a nonrandom fashion, with particular genetic loci occupying distinct spatial regions. This observation raises the question of whether the spatial organization of a chromosome governs its functions, such as recombination or transcription. We consider this general...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Avşaroğlu, Barış, Bronk, Gabriel, Li, Kevin, Haber, James E., Kondev, Jane
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111656/
https://ncbi.nlm.nih.gov/pubmed/27791086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1607103113
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