The airway epithelium undergoes metabolic reprogramming in individuals at high risk for lung cancer

The molecular determinants of lung cancer risk remain largely unknown. Airway epithelial cells are prone to assault by risk factors and are considered to be the primary cell type involved in the field of cancerization. To investigate risk-associated changes in the bronchial epithelium proteome that...

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Publicado en:JCI Insight
Autores principales: Rahman, S.M. Jamshedur, Ji, Xiangming, Zimmerman, Lisa J., Li, Ming, Harris, Bradford K., Hoeksema, Megan D., Trenary, Irina A., Zou, Yong, Qian, Jun, Slebos, Robbert J.C., Beane, Jennifer, Spira, Avrum, Shyr, Yu, Eisenberg, Rosana, Liebler, Daniel C., Young, Jamey D., Massion, Pierre P.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2016
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111517/
https://ncbi.nlm.nih.gov/pubmed/27882349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.88814
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