Integrative transcriptome network analysis of iPSC-derived neurons from schizophrenia and schizoaffective disorder patients with 22q11.2 deletion

BACKGROUND: Individuals with 22q11.2 Deletion Syndrome (22q11.2 DS) are a specific high-risk group for developing schizophrenia (SZ), schizoaffective disorder (SAD) and autism spectrum disorders (ASD). Several genes in the deleted region have been implicated in the development of SZ, e.g., PRODH and...

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發表在:BMC Syst Biol
Main Authors: Lin, Mingyan, Pedrosa, Erika, Hrabovsky, Anastasia, Chen, Jian, Puliafito, Benjamin R., Gilbert, Stephanie R., Zheng, Deyou, Lachman, Herbert M.
格式: Artigo
語言:Inglês
出版: BioMed Central 2016
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111260/
https://ncbi.nlm.nih.gov/pubmed/27846841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-016-0366-0
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