Integrative transcriptome network analysis of iPSC-derived neurons from schizophrenia and schizoaffective disorder patients with 22q11.2 deletion

BACKGROUND: Individuals with 22q11.2 Deletion Syndrome (22q11.2 DS) are a specific high-risk group for developing schizophrenia (SZ), schizoaffective disorder (SAD) and autism spectrum disorders (ASD). Several genes in the deleted region have been implicated in the development of SZ, e.g., PRODH and...

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Gepubliceerd in:BMC Syst Biol
Hoofdauteurs: Lin, Mingyan, Pedrosa, Erika, Hrabovsky, Anastasia, Chen, Jian, Puliafito, Benjamin R., Gilbert, Stephanie R., Zheng, Deyou, Lachman, Herbert M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111260/
https://ncbi.nlm.nih.gov/pubmed/27846841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-016-0366-0
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