Integrative transcriptome network analysis of iPSC-derived neurons from schizophrenia and schizoaffective disorder patients with 22q11.2 deletion

BACKGROUND: Individuals with 22q11.2 Deletion Syndrome (22q11.2 DS) are a specific high-risk group for developing schizophrenia (SZ), schizoaffective disorder (SAD) and autism spectrum disorders (ASD). Several genes in the deleted region have been implicated in the development of SZ, e.g., PRODH and...

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Foilsithe in:BMC Syst Biol
Main Authors: Lin, Mingyan, Pedrosa, Erika, Hrabovsky, Anastasia, Chen, Jian, Puliafito, Benjamin R., Gilbert, Stephanie R., Zheng, Deyou, Lachman, Herbert M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2016
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111260/
https://ncbi.nlm.nih.gov/pubmed/27846841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-016-0366-0
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