Integrative transcriptome network analysis of iPSC-derived neurons from schizophrenia and schizoaffective disorder patients with 22q11.2 deletion

BACKGROUND: Individuals with 22q11.2 Deletion Syndrome (22q11.2 DS) are a specific high-risk group for developing schizophrenia (SZ), schizoaffective disorder (SAD) and autism spectrum disorders (ASD). Several genes in the deleted region have been implicated in the development of SZ, e.g., PRODH and...

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Detalhes bibliográficos
Publicado no:BMC Syst Biol
Main Authors: Lin, Mingyan, Pedrosa, Erika, Hrabovsky, Anastasia, Chen, Jian, Puliafito, Benjamin R., Gilbert, Stephanie R., Zheng, Deyou, Lachman, Herbert M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111260/
https://ncbi.nlm.nih.gov/pubmed/27846841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-016-0366-0
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