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The kinase Grk2 regulates Nedd4/Nedd4-2-dependent control of epithelial Na(+) channels
Epithelial Na(+) channels mediate the transport of Na across epithelia in the kidney, gut, and lungs and are required for blood pressure regulation. They are inhibited by ubiquitin protein ligases, such as Nedd4 and Nedd4-2, with loss of this inhibition leading to hypertension. Here, we report that...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC511069/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15284439/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0402178101 |
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