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TRIM5α mediates the postentry block to N-tropic murine leukemia viruses in human cells

Murine leukemia viruses (MLVs) have been classified as N-tropic (N-MLV) or B-tropic (B-MLV), depending on their ability to infect particular mouse strains. The early phase of N-MLV infection is blocked in the cells of several mammalian species, including humans. This block is mediated by a dominant...

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Autors principals: Perron, Michel J., Stremlau, Matthew, Song, Byeongwoon, Ulm, Wes, Mulligan, Richard C., Sodroski, Joseph
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC511059/
https://ncbi.nlm.nih.gov/pubmed/15280539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403364101
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