Blocking Wnt Secretion Reduces Growth of Hepatocellular Carcinoma Cell Lines Mostly Independent of β-Catenin Signaling()

Aberrant activation of Wnt/β-catenin signaling plays a key role in the onset and development of hepatocellular carcinomas (HCC), with about half of them acquiring mutations in either CTNNB1 or AXIN1. However, it remains unclear whether these mutations impose sufficient β-catenin signaling or require...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neoplasia
Prif Awduron: Wang, Wenhui, Xu, Lei, Liu, Pengyu, Jairam, Kiran, Yin, Yuebang, Chen, Kan, Sprengers, Dave, Peppelenbosch, Maikel P., Pan, Qiuwei, Smits, Ron
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Neoplasia Press 2016
Pynciau:
Original article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110474/
https://ncbi.nlm.nih.gov/pubmed/27851986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2016.10.004
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg