HMGA1 Expression in Human Hepatocellular Carcinoma Correlates with Poor Prognosis and Promotes Tumor Growth and Migration in in vitro Models()

BACKGROUND: HMGA1 is a non-histone nuclear protein that regulates cellular proliferation, invasion and apoptosis and is overexpressed in many carcinomas. In this study we sought to explore the expression of HMGA1 in HCCs and cirrhotic tissues, and its effect in in vitro models. METHODS: We evaluated...

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Detalhes bibliográficos
Publicado no:Neoplasia
Main Authors: Andreozzi, Mariacarla, Quintavalle, Cristina, Benz, David, Quagliata, Luca, Matter, Matthias, Calabrese, Diego, Tosti, Nadia, Ruiz, Christian, Trapani, Francesca, Tornillo, Luigi, Fusco, Alfredo, Heim, Markus H, Ng, Charlotte KY, Pallante, Pierlorenzo, Terracciano, Luigi M, Piscuoglio, Salvatore
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2016
Assuntos:
Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110473/
https://ncbi.nlm.nih.gov/pubmed/27855356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2016.10.002
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