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Recruitment of the ArgR/Mcm1p repressor is stimulated by the activator Gcn4p: A self-checking activation mechanism

Transcription of the arginine biosynthetic gene ARG1 is repressed by the ArgR/Mcm1p complex in arginine-replete cells and activated by Gcn4p, a transcription factor induced by starvation for any amino acid. We show that all four subunits of the arginine repressor are recruited to ARG1 by Gcn4p in ce...

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Detalhes bibliográficos
Main Authors: Yoon, Sungpil, Govind, Chhabi K., Qiu, Hongfang, Kim, Soon-ja, Dong, Jinsheng, Hinnebusch, Alan G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC511042/
https://ncbi.nlm.nih.gov/pubmed/15289616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404652101
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