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Simultaneous Recruitment of Coactivators by Gcn4p Stimulates Multiple Steps of Transcription In Vivo

Transcriptional activation by Gcn4p is dependent on the coactivators SWI/SNF, SAGA, and Srb Mediator, which are recruited by Gcn4p and stimulate assembly of the preinitiation complex (PIC) at the ARG1 promoter in vivo. We show that recruitment of all three coactivators is nearly simultaneous with bi...

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Autors principals: Govind, Chhabi K., Yoon, Sungpil, Qiu, Hongfang, Govind, Sudha, Hinnebusch, Alan G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1156971/
https://ncbi.nlm.nih.gov/pubmed/15964818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.13.5626-5638.2005
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