Altered Glycosylation Patterns Increase Immunogenicity of a Subunit Hepatitis C Virus Vaccine, Inducing Neutralizing Antibodies Which Confer Protection in Mice

Hepatitis C virus (HCV) infection is a global health problem for which no vaccine is available. HCV has a highly heterogeneous RNA genome and can be classified into seven genotypes. Due to the high genetic and resultant antigenic variation among the genotypes, inducing antibodies capable of neutrali...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Li, Dapeng, von Schaewen, Markus, Wang, Xuesong, Tao, Wanyin, Zhang, Yunfang, Li, Li, Heller, Brigitte, Hrebikova, Gabriela, Deng, Qiang, Ploss, Alexander, Zhong, Jin, Huang, Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110194/
https://ncbi.nlm.nih.gov/pubmed/27630242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01462-16
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