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Attenuated Infectious Hematopoietic Necrosis Virus with Rearranged Gene Order as Potential Vaccine
The genome of infectious hematopoietic necrosis virus (IHNV), a salmonid novirhabdovirus, has been engineered to modify the gene order and to evaluate the impact on a possible attenuation of the virus in vitro and in vivo. By reverse genetics, eight recombinant IHNVs (rIHNVs), termed NxGy according...
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| 發表在: | J Virol |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5110182/ https://ncbi.nlm.nih.gov/pubmed/27681130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01024-16 |
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