Attenuated Infectious Hematopoietic Necrosis Virus with Rearranged Gene Order as Potential Vaccine

The genome of infectious hematopoietic necrosis virus (IHNV), a salmonid novirhabdovirus, has been engineered to modify the gene order and to evaluate the impact on a possible attenuation of the virus in vitro and in vivo. By reverse genetics, eight recombinant IHNVs (rIHNVs), termed NxGy according...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Rouxel, Ronan N., Tafalla, Carolina, Mérour, Emilie, Leal, Esther, Biacchesi, Stéphane, Brémont, Michel
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110182/
https://ncbi.nlm.nih.gov/pubmed/27681130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01024-16
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