Senp1 drives hypoxia-induced polycythemia via GATA1 and Bcl-xL in subjects with Monge’s disease

In this study, because excessive polycythemia is a predominant trait in some high-altitude dwellers (chronic mountain sickness [CMS] or Monge’s disease) but not others living at the same altitude in the Andes, we took advantage of this human experiment of nature and used a combination of induced plu...

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Publicat a:J Exp Med
Autors principals: Azad, Priti, Zhao, Huiwen W., Cabrales, Pedro J., Ronen, Roy, Zhou, Dan, Poulsen, Orit, Appenzeller, Otto, Hsiao, Yu Hsin, Bafna, Vineet, Haddad, Gabriel G.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2016
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110013/
https://ncbi.nlm.nih.gov/pubmed/27821551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151920
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