In vivo conditional deletion of HDAC7 reveals its requirement to establish proper B lymphocyte identity and development

Class IIa histone deacetylase (HDAC) subfamily members are tissue-specific gene repressors with crucial roles in development and differentiation processes. A prominent example is HDAC7, a class IIa HDAC that shows a lymphoid-specific expression pattern within the hematopoietic system. In this study,...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Azagra, Alba, Román-González, Lidia, Collazo, Olga, Rodríguez-Ubreva, Javier, de Yébenes, Virginia G., Barneda-Zahonero, Bruna, Rodríguez, Jairo, Castro de Moura, Manuel, Grego-Bessa, Joaquim, Fernández-Duran, Irene, Islam, Abul B.M.M.K., Esteller, Manel, Ramiro, Almudena R., Ballestar, Esteban, Parra, Maribel
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110011/
https://ncbi.nlm.nih.gov/pubmed/27810920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150821
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